寻求合作
[供] 德国大学提供骨再生用胶原蛋白
合作类型:技术     行业类别: 生物科学与健康     国家:德国
发布时间:2018年06月13日     过期时间:2021年03月09日     点击数:10

德国一所大学发现了一种使用胶原蛋白进行骨再生的方法。 与目前支持骨再生的程序相比,胶原蛋白可以局部应用。该大学向感兴趣的各方提供许可协议。

A German university found a method to use collagen for bone regeneration. In contrast to current procedures supporting bone regeneration collagen can be applied locally. The university offers a licensing agreement to interested parties.

 

Description     

Destruction of bone tissue after accidents, infections or tumor therapy requires a highly orchestrated regeneration process dependent on the presence of osteoblasts forming new bone. Since native bone harbors too few osteoblasts to enable a fast recovery of acutely injured bone tissue, stem cells need to give rise to new osteoblasts directly upon fracture or surgical treatment. In this regard, mesenchymal stem cells (MSCs) are commonly described to undergo differentiation into osteogenic cells types, such as osteoblasts.

 

Collagen is a natural part of the bone composition, and collagen membranes are in use to support bone regeneration. However, these membranes are based on collagen, which is completely dissolved before it is further processed to a membrane, and consequently has completely lost its natural structure and consequently some important biological functions.

 

Researchers of a German university have found a method to prepare collagen type I in its natural pore-like structure. They have shown that cultivation of human inferior turbinate stem cells (ITSCs) on collagen fibrils prepared by that method show osteogenic differentiation. Therefore, this collagen preparation method can be used for multiple applications in regenerative medicine, e.g. in bone fractures after accidents, joint replacement, dental prosthesis, or plastic surgery.

 

The university is offering a license agreement. Feasible partners are companies from the regenerative medicine, prosthesis fabrication or laboratory supplier. A licensee will have to develop a product from the prototype.

 

Type and Role of Partner Sought    

The university is offering a license agreement. Feasible partners are companies from:

- the regenerative medicine, working with stem cell therapies

- prosthesis production offering e.g. hip joints, that could be covered with the collagen

- laboratory supplier, who would offer the prepared collagen to laboratories.

 

A licensee will have to develop a product from the prototype. The prototype and all necessary data will be delivered by the inventors.

 

Licensing could include technical tasks if the production process needs to be optimized at industrial scale. Furthermore it could include joint work to optimize the technology.

【供】180121 TODE20180308002
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